Arthrotec-75 (Diclofenac Sodium/Misoprostol) Tablets Pfizer

Composition:

Each Arthrotec 75 mg tablet contains:

• Diclofenac Sodium: 50 mg
• Misoprostol: 200 mcg

Indications:

Arthrotec 75 mg is indicated for:

• The relief of signs and symptoms of osteoarthritis and rheumatoid arthritis in patients at high risk for developing NSAID-induced gastric ulcers.
• The prevention of gastric ulcers in patients who require long-term NSAID therapy.

Dosage:

• The recommended dosage for adults is one tablet (75 mg) taken orally, two to three times daily, depending on the severity of the condition and the patient's response to treatment.
• It is advisable to take the medication with food or milk to minimize gastrointestinal irritation.
• Dosage adjustments may be necessary for elderly patients or those with renal impairment.

Contraindications:

Arthrotec 75 mg is contraindicated in the following situations:

• Known hypersensitivity to diclofenac, misoprostol, or any other components of the formulation.
• Active or history of peptic ulcer disease or gastrointestinal bleeding.
• Severe renal impairment or hepatic impairment.
• Pregnant women, especially during the third trimester, due to the risk of uterine contractions and potential harm to the fetus.
• Patients with a history of inflammatory bowel disease or other gastrointestinal disorders that may be exacerbated by NSAIDs.

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