Asomex-5 (S-Amlodipine) 5mg Tablets
What is Asomex-5?
Asomex-5 contains S-Amlodipine 5mg, a next-generation calcium channel blocker used to treat high blood pressure (hypertension) and chest pain (angina). It is the purified, active form of the widely used amlodipine — delivering the same powerful blood pressure control at half the conventional dose, which means fewer side effects and better tolerability for most patients.
S-Amlodipine works by relaxing and widening blood vessels, making it easier for the heart to pump blood efficiently — lowering blood pressure and reducing the heart's workload.
What It Treats
- High blood pressure (hypertension) — primary and secondary
- Chronic stable angina (chest pain due to reduced blood flow to the heart)
- Vasospastic angina (Prinzmetal's angina — chest pain caused by coronary artery spasm)
- Prevention of cardiovascular events in high-risk patients
- Used as part of combination therapy for difficult-to-control hypertension
How It Works S-Amlodipine blocks calcium channels in the walls of blood vessels and the heart. Calcium causes muscles to contract — by blocking its entry, S-Amlodipine causes the blood vessel walls to relax and widen (dilate). This:
- Lowers blood pressure by reducing resistance in the arteries
- Increases blood and oxygen supply to the heart
- Reduces the frequency and severity of angina episodes
- Protects the heart and kidneys from long-term damage caused by sustained high blood pressure
Why Asomex-5 (S-Amlodipine) Over Regular Amlodipine?
| Feature | Regular Amlodipine (10mg) | S-Amlodipine / Asomex-5 (5mg) |
|---|---|---|
| Active component | Mix of R + S forms | Pure S-form only |
| Effective dose | 10mg | 5mg |
| Ankle swelling (edema) | More common | Significantly reduced |
| Flushing & headache | More frequent | Less frequent |
| Heart rate increase | More likely | Lower incidence |
| Tolerability | Standard | Superior |
| Blood pressure control | Effective | Equally effective |
Dosage Guide
| Patient Group | Dose | Frequency |
|---|---|---|
| Adults – Hypertension | 2.5mg – 5mg | Once daily |
| Adults – Angina | 5mg | Once daily |
| Elderly patients | Start at 2.5mg | Once daily |
| Patients with liver disease | Start at 2.5mg (with caution) | Once daily |
| Children | Not routinely recommended | Consult doctor |
Asomex-5 is a once-daily tablet that can be taken with or without food. Take it at the same time each day for consistent blood pressure control. Do not stop taking it suddenly without consulting your doctor, even if you feel well — high blood pressure often has no symptoms.
Why Choose Asomex-5?
- Clinically superior tolerability – fewer side effects than regular amlodipine
- Once-daily dosing – simple, easy to maintain routine
- Effective at lower dose – 5mg delivers what 10mg regular amlodipine does
- Reduced ankle swelling – major advantage for patients troubled by edema
- Dual action – treats both hypertension and angina
- Long-acting – provides smooth, sustained 24-hour blood pressure control
- Suitable for elderly – well tolerated in older patients
- Kidney and heart protective – helps prevent long-term organ damage
Who Should Avoid Asomex-5?
- Patients with known allergy to amlodipine or any dihydropyridine calcium channel blocker
- Patients with severe low blood pressure (hypotension)
- Those with severe aortic stenosis (narrowing of the heart's aortic valve)
- Cardiogenic shock patients
- Pregnant or breastfeeding women without doctor's approval
Possible Side Effects Asomex-5 is well tolerated by most patients. Possible side effects include:
Common:
- Ankle or leg swelling (less frequent than regular amlodipine)
- Headache
- Flushing (feeling of warmth or redness)
- Dizziness
- Fatigue
Less Common:
- Palpitations
- Nausea or stomach discomfort
- Skin rash
Rare but Serious — Seek Immediate Medical Help:
- Severe chest pain (especially in the first days of treatment)
- Significant drop in blood pressure
- Severe skin reactions
- Jaundice (yellowing of skin or eyes — sign of liver involvement)
Drug Interactions Tell your doctor or pharmacist if you are taking:
- Other antihypertensives – additive blood pressure lowering effect
- CYP3A4 inhibitors (e.g. clarithromycin, ketoconazole, grapefruit juice) – may increase S-Amlodipine levels in the blood
- CYP3A4 inducers (e.g. rifampicin, carbamazepine) – may reduce effectiveness
- Simvastatin – S-Amlodipine may increase simvastatin blood levels; dose adjustment may be needed
- Cyclosporine – blood levels may be increased
- Tacrolimus – monitor levels closely if taken together
Avoid grapefruit juice while on this medication — it can increase drug levels and amplify side effects.
Storage Instructions
- Store below 30°C in a cool, dry place
- Protect from direct sunlight and moisture
- Keep out of reach of children
- Do not use after the expiry date on the pack