Bonduretic (Amiloride Hydrochloride & Hydrochlorothiazide) Tablets
What is Bonduretic?
Bonduretic is a fixed-dose combination diuretic (water tablet) that brings together:
- Amiloride Hydrochloride 5mg — a potassium-sparing diuretic that helps the kidneys remove excess sodium and water while retaining potassium
- Hydrochlorothiazide 50mg — a thiazide diuretic that increases urine production to reduce fluid build-up and lower blood pressure
Together, these two ingredients complement each other perfectly. Hydrochlorothiazide removes fluid effectively but can cause potassium loss — amiloride counteracts this by retaining potassium, making Bonduretic a safer and more balanced option than using either drug alone.
What is Bonduretic Used For?
- High blood pressure (hypertension) — reduces blood pressure by removing excess fluid from the bloodstream
- Oedema (fluid retention) — relieves swelling caused by heart failure, liver disease, or kidney conditions
- Congestive heart failure — helps reduce the fluid overload that strains the heart
- Liver cirrhosis with ascites — manages fluid accumulation in the abdomen
- Prevention of potassium loss — the amiloride component protects against the low potassium (hypokalaemia) that thiazide diuretics can cause
How to Take Bonduretic Tablets
- Take as directed by your doctor — typically once daily in the morning
- Take with or after food to reduce the risk of stomach upset
- Take it early in the day to avoid frequent urination at night
- Swallow whole with a glass of water
- Try to take it at the same time each day for consistent effect
- Do not stop taking Bonduretic suddenly without consulting your doctor
💧 Stay well hydrated — while Bonduretic removes excess fluid, it is still important to drink adequate water daily unless your doctor advises otherwise.
Who Should NOT Take Bonduretic?
Do not take Bonduretic if you have:
- High potassium levels (hyperkalaemia) — amiloride retains potassium, so elevated potassium is dangerous
- Low potassium or sodium levels already being treated
- Severe kidney impairment or kidney failure
- Severe liver disease
- Addison's disease (adrenal insufficiency)
- Anuria (inability to produce urine)
- Known allergy to amiloride, hydrochlorothiazide, sulphonamides, or any ingredient in the tablet
- Currently taking other potassium-sparing diuretics or potassium supplements
Common Side Effects of Bonduretic
Most patients tolerate Bonduretic well when taken correctly. Possible side effects include:
| Side Effect | Frequency |
|---|---|
| Increased urination (especially early on) | Very common |
| Dizziness or lightheadedness | Common |
| Nausea or stomach upset | Common |
| Headache | Common |
| Muscle cramps or weakness | Less common |
| Dry mouth or thirst | Less common |
| High potassium (hyperkalaemia) | Less common |
| Low sodium (hyponatraemia) | Less common |
| Skin sensitivity to sunlight | Rare |
| Gout flare-up | Rare |
Contact your doctor immediately if you notice an irregular heartbeat, severe muscle weakness, difficulty breathing, or signs of an allergic reaction such as rash, itching, or facial swelling.
Important Drug Interactions
Bonduretic can interact with several commonly used medicines. Always inform your doctor or pharmacist if you are taking:
- ACE inhibitors or ARBs (e.g. lisinopril, losartan) — increased risk of high potassium
- NSAIDs (e.g. ibuprofen, diclofenac) — may reduce Bonduretic's effectiveness and affect kidney function
- Lithium — Bonduretic can increase lithium levels in the blood, raising toxicity risk
- Digoxin — diuretics can affect digoxin levels and cardiac effects
- Diabetes medications — hydrochlorothiazide may affect blood sugar control
- Potassium supplements — avoid unless specifically prescribed alongside Bonduretic
Why Buy Bonduretic from Amkamed Pharmaceuticals?
At Amkamed Pharmaceuticals, we are committed to delivering safe, genuine, and affordable medicines to your doorstep:
- 🏥 100% authentic, quality-assured medications
- 🚚 Fast, discreet, and reliable nationwide delivery
- 💊 Licensed pharmacists on hand for support and guidance
- 🔒 Secure, confidential, and easy online ordering
- 📋 Strict prescription verification to protect your health