Co-Mepiryl (glimepiride & Metformin) 2/500mg

Co-Mepiryl 2/500mg is a dual-action oral tablet for adults with type 2 diabetes whose blood sugar is not adequately controlled by either drug alone. It combines two proven medicines — glimepiride (a sulfonylurea) and metformin — in a single convenient tablet taken once or twice daily with meals.

How it works

Glimepiride 2mg

Stimulates the pancreas to release more insulin, lowering blood glucose after meals.

Metformin 500mg

Reduces glucose production in the liver and improves how the body uses insulin.

Key benefits

Dosage & use

Take one tablet by mouth with the first main meal of the day, or as directed by your doctor. Swallow whole with water — do not crush or chew. The dose may be adjusted by your healthcare provider based on your blood sugar response.

Important safety information

• Not for type 1 diabetes or diabetic ketoacidosis
• Avoid if you have severe kidney or liver disease
• Can cause low blood sugar (hypoglycaemia) — carry a glucose source
• Inform your doctor before surgery or if you drink alcohol regularly
• This medicine requires a valid prescription

Common side effects

Side effects are often mild and improve after the first few weeks. Taking the tablet with food helps reduce stomach-related effects. Always consult your pharmacist or doctor if symptoms persist.